Right before taking this medication, tell your physician or pharmacist When you are allergic to any of its elements; or to opioid pain relievers (which include morphine); or When you've got some other allergies.

Narcotics might develop adverse reactions which may obscure the scientific system of clients with head injuries.

Get health-related aid immediately For those who have any incredibly significant Negative effects, which includes: sluggish/shallow respiration, seizures.

Take this medication by mouth. Stick to the Instructions on the prescription label. You can take it with or without food stuff. If it upsets your abdomen, acquire it with foods. Utilize a specifically marked spoon or container to evaluate Each and every dose.

Animal reproduction experiments have not been conducted Together with the drug combination-promethazine and codeine. It is not regarded no matter if this drug blend might cause fetal hurt when administered to your Expecting girl or can influence replica capacity.

) Paradoxical Reactions- Hyperexcitability and irregular movements have already been claimed in patients adhering to one administration of promethazine HCl. Consideration need to be specified towards the discontinuation of promethazine HCl and also to using other medicines if these reactions come about. Respiratory depression, nightmares, delirium, and agitated actions have also been reported in A few of these sufferers.

Unique research to test the motion of the drug on parturition, lactation, and growth of the animal neonate weren't completed, but a normal preliminary review in rats indicated no impact on these parameters.

Decreased Seizure Threshold – Promethazine may reduce seizure threshold. It ought to be employed with caution in persons with seizure disorders or in individuals that are utilizing concomitant prescription drugs, for instance narcotics or nearby anesthetics, which may also have an affect on seizure threshold.

Codeine is transformed into a solid opioid drug (morphine) in your body. In a lot of people, this alteration transpires speedier and much more wholly than standard, which raises the danger of incredibly significant Unwanted side effects.

Explain to your medical professional In case you are pregnant or think you may be Expecting. Through pregnancy, this product isn't suggested. It might hurt an unborn baby. Speak with your medical professional about the risks and benefits of this medication. See also Warning portion.

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This medication may well interfere with specified lab checks (such as some pregnancy tests, blood Promethazine codeine syrup sugar assessments, amylase/lipase ranges), probably causing Untrue test results. Make certain lab personnel and all of your doctors know you use this drug.

Codeine and its salts are well absorbed adhering to both equally oral and parenteral administration. Codeine is about two/3 as successful orally as parenterally. Codeine is metabolized principally from the liver by enzymes in the endoplasmic reticulum, exactly where it undergoes O-demethylation, N-demethylation, and partial conjugation with glucuronic acid.

Bear in mind this medication has long been prescribed simply because your health practitioner has judged the benefit to you personally is greater than the chance of Unintended effects. Many people working with this medication don't have severe side effects.